Ovarian dysfunction, unspecified. Ovarian dysfunction, unspecified
Conditions
Interventions
Intervention 1: Prescription of 2tablet ( 40mg) tamoxifenfir 5 days from day 3-7 of menstrual cycle, serial sonography in day 12-16 was done for evaluation of endometrial thickness and pattern and num
Treatment - Drugs
Prescription of 2tablet ( 40mg) tamoxifenfir 5 days from day 3-7 of menstrual cycle, serial sonography in day 12-16 was done for evaluation of endometrial thickness and pattern and number of mature fo
Prescription of 150mg clomiphen citrate for 5 days from day 3-7 of menstrual cycle, serial sonography in day 12-16 was done for evaluation endometrial thickness and pattern and number of mature follic
Sponsors
Vice chancellor for research-Guilan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
15 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criterion: infertile women with ovulation disorders without other cause of infertility. Exclusion criteria: abnormal semen analysis and HSG or laparoscopy; age over 40; myoma; hyperprolactinema; FSH over12; hypothyroidism; hyperthyroidism; previous history of induction of ovulation; renal & liver disease and contraindication of clomiphen citrate and tamoxifen.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pregnancy rate. Timepoint: End of menstural cycle. Method of measurement: Serum BhCG. | — |
Secondary
| Measure | Time frame |
|---|---|
| Abortion rate. Timepoint: End of menstrual cycle. Method of measurement: The incidence of menstrual bleeding and new.;Multigestation rate. Timepoint: End of menstrual cycle. Method of measurement: Sonography.;Ovarian hyperstimulation syndrome. Timepoint: End of menstrual cycle. Method of measurement: Clinical and ultrasound.;Side effects such as headaches, dizziness, blurred vision, nausea and vomiting. Timepoint: During the treatment cycle. Method of measurement: Ask the patient. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed