Effect of Portulaca oleracea seeds on indicators of inflammation,8-isoprostane and lung function in women with asthma

Effect of Portulaca oleracea seeds on indicators of inflammation,8-isoprostane and lung function in women with asthma : a randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201206094105N7

Enrollment

Registered

2012-07-05

Start date

2012-06-25

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma. moderate asthms

Interventions

In control group, Patients have their treatment protocol and drink two glasses of water in a day for 8 weeks.

Intervention 1: In the interventional group,patients have treatment protocol and daily take 10 g Portulaca oleracea seeds in two doses (5 gm) in morning (fasting) and before dinner with a glass of wat

Treatment - Drugs

In the interventional group,patients have treatment protocol and daily take 10 g Portulaca oleracea seeds in two doses (5 gm) in morning (fasting) and before dinner with a glass of water .

Eligibility

Sex/Gender

Female

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: • female • Age 18 years and above •having Moderate asthma for at least 1 year as diagnosed by a physician according the Gina guideline Exclusion criteria: • Smoking • having other lung disorders and respiratory tract infections • Pregnant or lactating • kidney, liver or cardiovascular disease • taking any multivitamin and mineral and dietary supplements containing antioxidants and omega-3 in 2 months ago • Any change in drug type and dosage • having a history of oxalate stones • having a exacerbation in last month that led to hospitalization • follow a diet • taking contraceptive pills

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
IL-4, TNF_a and nitric oxide metabolites (nitrite and nitrate). Timepoint: before and after of intervention. Method of measurement: sputum sample.;8 - Isoprostane. Timepoint: before and after of intervention. Method of measurement: sputum sample.;PEF and FEV1. Timepoint: before and after of intervention. Method of measurement: spirometer.	—

Secondary

Measure	Time frame
Food intake. Timepoint: Before and after of intervention. Method of measurement: 24-hour dietary recall.;BMI. Timepoint: Before and after of intervention. Method of measurement: Scales and meters.	—

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026