subcutaneous tramadol and methadone in post laparatomy pain control

Comparison effect of local subcutaneous tramadol and methadone in post laparatomy pain control

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120605009948N3

Enrollment

Registered

2018-09-19

Start date

2016-11-21

Completion date

Unknown

Last updated

2018-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper abdominal laparotomy. Superficial injury of abdomen, lower back, pelvis and external genitals

Interventions

Intervention 1: Intervention group: Tramadol (100 mg of tramadol diluted with normal saline to 10 cc). Intervention 2: Control group: Methadone (Methadone at a dose of 70 µg / kg diluted with normal s

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: • Patients who are electively underwent laparotomy. • Patients undergoing general anesthesia. • Patients with no Epidural catheter. •Do not use analgesic at least 6 hours before surgery

Exclusion criteria

Exclusion criteria: Pregnancy Having Diabetes mellitus or chronic renal, liver or heart disease Previous laparatomy Opium addiction Chronic psychological disease Chronic pain disorders

Design outcomes

Primary

Measure	Time frame
Intensity of pain. Timepoint: 1 hours after surgery, 6 hours after surgery, 12 hours after surgery, 18 hours after surgery and 24 hours after surgery. Method of measurement: Using VAS and NPS criteria.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMostafa Hojaty

Tabriz University of Medical Sciences

hojatmo@gmail.com+98 41 3334 1994

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026