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Effect of nebulized ketamine on reducing pain of nasogastric tube

Comparison of nebulized ketamine and distilled water in reducing nasogastric tube placement pain on Imam Khomeini hospital emergency department’s patients in 2012

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT201206029162N2
Enrollment
60
Registered
2013-01-29
Start date
2012-03-19
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain Management in nasogastric tube insertj. Medical procedure, unspecified, Insertion of gastric or duodenal sound

Interventions

Intervention 1: Control group: Nebulizing research syringe (1cc distilled water) plus 2cc distilled water Then insertion of NG Tube in standard manner. Intervention 2: Intervention group: Nebulizing r
Treatment - Drugs
Control group: Nebulizing research syringe (1cc distilled water) plus 2cc distilled water Then insertion of NG Tube in standard manner
Intervention group: Nebulizing research syringe (1cc Ketamine =50 mg) plus 2cc distilled water Then insertion of NG Tube in standard manner

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 149 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients admitted to emergency department of Imam Khomeini hospital which needs NG tube; Age greater than or equal to 15 years Exclusion Criteria: inability to express the pain(eg,Altered Mental Status,Language Barrier,Dementia, intoxication); Severe Hypertension (BP> 180/110); Unstable Multiple Trauma patients (SBP < 90mmhg, GCS<14, needs operating room at time of entrance); Pregnancy (visible or declared by patient); Use of Opium in last 6 hours; Opium addiction; Coronary Artery Disease (declared by patient); Decompensated Heart failure (Rales at lungs exam); Allergy to Ketamine; Reactive Airway Diseases; Abnormal Airway Anatomy ; Nasal fracture (in last week); deformity & bleeding; Patients who doesn't sign the consent form

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain of insertion of NG Tube. Timepoint: After insertion of tube. Method of measurement: Asking the patient.;Complications of insertion of nasogastric tube. Timepoint: continuously from insertion of tube until 60 min after procedure. Method of measurement: observation of complication such as: nausea, vomiting, nose bleed, hypoxia, tracheal insertion.;Complication of drug. Timepoint: continuously from begining of the nebulization of drug until 60 min after procedure. Method of measurement: Observation of Ketamine complication such as Hallucination, Nausea, vomiting, hypertension, agitation and seizure.

Secondary

MeasureTime frame
Arterial O2 Saturation. Timepoint: At the begining of the procedure until 30 min after that. Method of measurement: By pulse-oxymeter.;Heart Rate. Timepoint: At the begining of the procedure until 30 min after that. Method of measurement: By pulse-oxymeter.;Systolic BP. Timepoint: At the begining of the procedure until 30 min after that. Method of measurement: Sphygmomanometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Nejati M.D.

Tehran University of Medical Sciences

anejati@tums.ac.ir, a-nejati@tums.ac.ir, nejati.am@gmail.com+98 21 6119 2240

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026