infertility. Female infertility
Conditions
Interventions
Intervention 1: Group A: a daily dose of Buserelin 500 µg given SC and commenced 21th day of cycle, and vaginal ultrasonography continued onward until estradiol on the 2nd day of cycle. Intervention 2
Treatment - Drugs
Group A: a daily dose of Buserelin 500 µg given SC and commenced 21th day of cycle, and vaginal ultrasonography continued onward until estradiol on the 2nd day of cycle.
Group B: GnRH antagonist was administered. Ovarian stimulation was started on the 2nd day of the cycle by SC injection of 75 IU of FSH daily. On the 6th day of stimulation, 0.25 mg Cetrorelix was init
Sponsors
Isfahan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
No minimum to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: undergoing assisted reproduction techniques (ARTs) for the first time, age =35years and serum FSH level =10 IU/liter. Exclusion criteria: women with the previous history of IVF or ICSI; patients who had hyperprolactinemia, thyroid dysfunction, uterine abnormality, severe endometriosis and secondary infertility.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ovarian hyperstimulation syndrome. Timepoint: 10 days after HCG injection and during primary Trimester. Method of measurement: as presence of enlarged ovarian cysts more than 12 by 12 cm, ascites, pleural and/or pericardial effusion, electrolyte imbalance ,hypovolemia, and hypovolemic shock.;Fertility. Timepoint: after primary Trimester. Method of measurement: ultrasonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of retrieved oocytes. Timepoint: 2 weeks after intervention. Method of measurement: number of retrieved oocytes in retrieval day. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSetare Nasiri Zeydi
Isfahan University of Medical Sciences
Outcome results
None listed