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In comparing the effect of antidepressant treatment

Comparison of Citalopram and Venlafaxine in the treatment of patients with major depressive disorder

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201205289891N1
Enrollment
80
Registered
2012-07-19
Start date
2011-06-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major Depressive Disorder. Depressive episode

Interventions

Intervention 1: Group 1 will be treated with citalopram 20mg/day.After one month if the doctor considers the patient needs extra doses of drug,the given dose will be increased to 40 mg/day. Interventi
Treatment - Drugs
Group 1 will be treated with citalopram 20mg/day.After one month if the doctor considers the patient needs extra doses of drug,the given dose will be increased to 40 mg/day
Group 2 will be treated with venlafaxin 75mg/day.After one month if the doctor considers the patient needs extra doses of drug,the given dose will be increased to 150mg/day

Sponsors

Islamic Azad University of Yazd
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: a respectal psychiatrist confirms a patient has major depressive disorder based on DSM-IV criteria exclusion criteria:patiants who have not used any antidepressant drugs within the last 2 months ; Hypertension ; Mental retardation ; drug abuse and addiction

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Severity of depression. Timepoint: weeks 0, 4 and 8. Method of measurement: Beck Depression Inventory.

Secondary

MeasureTime frame
Side effects. Timepoint: week 8. Method of measurement: check list by filling out the patient's medication side effects.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSanaz Azizi

Islamic Azad University of Yazd

Sanaz.Azizi@gmail.com+98 35 1821 0543

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026