minocycline on the neurological outcome

The effect of minocycline on the neurological outcome of spinal cord injury patients

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120527009878N15

Enrollment

Registered

2022-09-10

Start date

2022-10-07

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal Injury. Other and unspecified injury of lumbar and sacral spinal cord

Interventions

Intervention 1: Intervention group: will receive bolus infusion of methylprednisolone 33 mg/kg in 15 minutes intravenous and after 45 minutes they will receive 4,5 mg/kg infusion of methylprednisolon

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with spinal cord injury from T10 to L2 Patients with age of 18 to 60 Frankle grade A to D

Exclusion criteria

Exclusion criteria: Patients older or younger than 17-60; Patients with head trauma and GCS score lower than 13 Reaction to Minocycline use Spinal cord injury out of T10 to L2 Trials

Design outcomes

Primary

Measure	Time frame
Investigation of Neurological status based on Frankel Grade. Timepoint: At admission and 6-month period after admission. Method of measurement: Based on Frankel grade.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Farhad Mirzaei

Tabriz University of Medical Sciences

golzar.farhad@yahoo.com+98 41 3334 0830

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026