systemic Tranexamic acid injection with topical in spinal surgery

Comparison of systemic Tranexamic acid injection with topical in reduction of bleeding during and after spinal surgery

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120527009878N14

Enrollment

100

Registered

2021-12-19

Start date

2021-04-21

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effect of Tranexamic Acid for bleeding in Spinal Surgery. Hemorrhagic condition, unspecified

Interventions

Intervention 1: Intervention group: Systemic tranexamic acid in first before the skin incision 10 mg per kg body weight as the initial bolus dose and then 1 mg per kg body weight every hour until the

Eligibility

Sex/Gender

All

Age

15 Years to 75 Years

Inclusion criteria

Inclusion criteria: Candidates to the spinal fixation surgery Agreed to participator

Exclusion criteria

Exclusion criteria: History of abnormal bleeding Platelet less than 150 thousands History of Thrombosis Consumption of interfering drugs with blood Homeostasis Overweight (BMI>30)

Design outcomes

Primary

Measure	Time frame
Bleeding. Timepoint: During surgery till 48 hours after surgery. Method of measurement: Number of pads and amount of suction blood during surgery.	—

Secondary

Measure	Time frame
Length of hospitalization during laminectomy and in spinal fusion. Timepoint: During surgery and duration of hospitalization after surgery. Method of measurement: Duration of hospitalization in hospital days.;The amount of blood collected in hemovac in patients undergoing laminectomy and in spinal fusion. Timepoint: Duration of hospitalization after surgery. Method of measurement: The amount of blood accumulated in CC.	—

Measure

Time frame

Length of hospitalization during laminectomy and in spinal fusion. Timepoint: During surgery and duration of hospitalization after surgery. Method of measurement: Duration of hospitalization in hospital days.;The amount of blood collected in hemovac in patients undergoing laminectomy and in spinal fusion. Timepoint: Duration of hospitalization after surgery. Method of measurement: The amount of blood accumulated in CC.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Farhad Mirzaei

Tabriz University of Medical Sciences

golzar.farhad@yahoo.com+98 41 3334 7054

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026