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Evaluation of thyroid function in prognosis of traumatic brain injury

Evaluation of thyroid function tests and effect of levothyroxin in prognosis of traumatic brain injury

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120527009878N13
Enrollment
100
Registered
2020-02-08
Start date
2018-03-21
Completion date
Unknown
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head Trauma. Diffuse traumatic brain injury

Interventions

Intervention group: Patients 3 day of after traumatic brain injury will receive twice daily levothyroxin 50 mg and this dose will continue for 6 weeks.

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 65 Years

Inclusion criteria

Inclusion criteria: patients 16 to 65 years of age Having informed consent to participate in the study Diffuse axonal injury in patients with head injuries

Exclusion criteria

Exclusion criteria: Receiving NSAIDS or corticosteroids history of cardiac, respiratory, neuromuscular, hepatic or renal diseases, history of brain injuries Having out and intracranial space-occupying lesions

Design outcomes

Primary

MeasureTime frame
Consciousness in patients. Timepoint: daily until discharge. Method of measurement: Glasgow coma scale.;Glasgow Outcome Scale. Timepoint: pre-intervention and weekly until discharge. Method of measurement: Glasgow Outcome Scale questionnaire.;Disability Rating Scale (DRS) scoring. Timepoint: pre-intervention and weekly until discharge. Method of measurement: Disability Rating Scale questionnaire.

Secondary

MeasureTime frame
Mortality rate. Timepoint: In duration 6 weeks after traumatic brain injury. Method of measurement: Questionnaire on complications after traumatic brain injury.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Firoz Salehpoor

Tabriz University of Medical Sciences

salehpourf@tbzmed.ac.ir+98 41 1334 0830

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026