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The effect of medication on reducing lumbar pain

Role of clonidine in management of pain after lumbar discectomy

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120527009878N11
Enrollment
60
Registered
2019-10-20
Start date
2640-01-26
Completion date
Unknown
Last updated
2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-procedural Pain. Other acute postprocedural pain

Interventions

Intervention 1: Intervention group: Clonidine produced by Zahravi Tabriz Company will be given orally to the patients in the form of 0.2 mg tablet twice daily. Intervention 2: Control group: Placebo p

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 70 years Weight 60 to 80 kg Having satisfaction Adherence of clinical signs and symptoms to MRI findings The presence of a disc in a lumbar space in an MRI

Exclusion criteria

Exclusion criteria: History of lumbar surgery Drug or Alcohol Addiction Pregnancy and lactation Previous use of the same drugs Seizures and other neurological diseases Intervention over a diskette only involves the use of a discectomy or diskette over a disk space Use of other medications the day before or after surgery (unwanted) The patient's disability is due to retardation, aphasia, visual impairment, and other things that prevent the patient from communicating. The patient's over-standard need for opioid and analgesic neuropathic drugs History of obstructive peripheral vascular disease

Design outcomes

Primary

MeasureTime frame
Post-operative pain. Timepoint: Clonidine used in capsule form and 2 hours before surgical intervention in the case group will be given to patients. After surgery for the first 24 hours and at the end of 6 hours, one physician who is blind to the study will record the parametric / VAS pain rate in the sheet. The amount of Opioid ingestion in the first 24 hours after surgery will also be measured for each patient. Method of measurement: Using VAS (virtual analogue scale) to measure pain in the lower extremities and wrists of patients receiving clonidine and placebo.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJavad Aghazade

Tabriz University of Medical Sciences

jaghazadeh56@yahoo.com+98 41 3333 8397

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026