Obesity. Obesity, unspecified
Conditions
Interventions
Intervention 1: The first intervention group: low calorie diet and 100 g/day yogurt enriched with 1000 IU 25OHD3. Intervention 2: The second intervention group: low calorie diet and 100 g/day probioti
Sponsors
Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Willingness to lose weight Age between 18 and 60 Body mass index (BMI) between 29 and 51 Filling the consent form of the present project Absence of associated co-morbidities (insulin dependent diabetes, chronic kidney disease, cancer and anemia) Absence of breast-feeding, pregnancy or menopause No history of hormone disorders including: hypothyroid, hyperthyroid, polycystic ovary syndrome (PCOS), breast and ovary cyst No intake of vitamin D for 1 months before the study initiation No antibiotic treatment for the last 1 month No intake of probiotic, prebiotic and synbiotic supplement and/ or probiotic, prebiotic and synbiotic enriched products 1 month before the study initiation
Exclusion criteria
Exclusion criteria: Individuals who had allergy to yogurt Individuals who use certain regimens or weight loss regimens Individuals who use any kind of vitamin supplements Individuals who use any kind of weight loss drug or supplement women who use contraceptive drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 25(OH)D3. Timepoint: In base line (before intervention) and 10 months after the beginning of intervention. Method of measurement: By using ELISA Kit.;Ghrelin hormone. Timepoint: In base line (before intervention) and 10 months after the beginning of intervention. Method of measurement: By using ELISA Kit.;Peptid YY hormone. Timepoint: In base line (before intervention) and 10 months after the beginning of intervention. Method of measurement: By using ELISA Kit.;GLP-1 hormone. Timepoint: In base line (before intervention) and 10 months after the beginning of intervention. Method of measurement: By using ELISA Kit.;Waist Circumference. Timepoint: In base line (before intervention) and 10 months after the beginning of intervention. Method of measurement: In term of centimeter by Tape measure.;Body Fat Mass. Timepoint: In base line (before intervention) and 10 months after the beginning of intervention. Method of measurement: in term of kg, by using body analyzer instrument.;Hip Circumference. Timepoint: In base line (before intervention) and 10 months after the beginning of intervention. Method of measurement: In term of centimeter by Tape measure. | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum LDL. Timepoint: before and after 10 weeks. Method of measurement: by using Friedewald equation.;Serum HDL. Timepoint: before and after 10 weeks. Method of measurement: by using biochemical kits (mono bind ELISA kit).;Serum fasting blood sugar. Timepoint: before and after 10 weeks. Method of measurement: by using biochemical kits (mono bind ELISA kit).;Serum total cholostrol. Timepoint: before and after 10 weeks. Method of measurement: by using biochemical kits (mono bind ELISA kit).;Serum Total triglycerides. Timepoint: before and after 10 weeks. Method of measurement: by using biochemical kits (Monobind ELISA kit). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShima Hajipour
Kermanshah University of Medical Sciences
Outcome results
None listed