Comparing the effectiveness of spironolactone solution with clindamycin solution in patients with acne

Comparison of the efficacy of spironolactone 5% solution with clindamycin 2% solution in patients with mild to moderate acne vulgaris

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120524009844N12

Enrollment

Registered

2024-06-18

Start date

2024-06-21

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild to moderate acne vulgaris. Acne vulgaris

Interventions

Intervention 1: Intervention group: The first group will be treated with a spironolactone 5% solution topically on acne lesions up to a distance of one centimeter around the lesion for 8 weeks. Interv

Eligibility

Sex/Gender

All

Age

15 Years to 35 Years

Inclusion criteria

Inclusion criteria: Mild to moderate acne vulgaris Age 15 to 35 years

Exclusion criteria

Exclusion criteria: Allergy and sensitivity to the drugs used in the study worsening of lesions suffering from diseases that cause acne and medicinal acne severe cases of acne (cases of nodules and cysts) use of anti-acne treatment in the last 4 weeks pregnancy

Design outcomes

Primary

Measure	Time frame
Total acne Lesions counting. Timepoint: Once every four weeks. Method of measurement: Clinical examination and observation.;Acne Severity Index. Timepoint: Once every four weeks. Method of measurement: Clinical examination and observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Amirnia

Tabriz University of Medical Sciences

amirniam@tbzmed.ac.ir+98 41 1540 6612

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026