Effect of high dose atorvastatin in preventing myocardial infarction following coronary angioplasty

Effect of high dose atorvastatin within 24 hours before elective percutaneous coronary intervention on periprocedural myocardial infarction in patients treated at Imam Khomeini hospital between September 2010 to March 2010

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201205209768N1

Enrollment

190

Registered

2012-08-16

Start date

2010-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Myocardial Infarction. Acute myocardial infarction

Interventions

Intervention 1: 80 mg oral atorvastatin within 24 hours before PCI. Intervention 2: 80 mg oral placebo within 24 hours before PCI.

Treatment - Drugs

Placebo

80 mg oral atorvastatin within 24 hours before PCI

80 mg oral placebo within 24 hours before PCI

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Candidates for elective coronary angioplasty with stable angina at Imam Khomeini hospital. Exclusion criteria:: 1- Previous CABG 2- Need for emergency primary PCI (3+ or stenosis > 2 cm2 7- serum creatinine > 1.2 mg/dl 8- History of liver dysfunction or rise of hepatic aminotransferases>3 folds 9- ejection fraction<30%

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Myocardial infarction. Timepoint: 6 & 12 hours after angioplasty. Method of measurement: Serum levels of CK-MB and Troponin I.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli pasha Meisami

Tehran University of Medical Sciences

meysamie@tums.ac.ir+216 6404377

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 10, 2026