chronic coronary syndrome. Atherosclerotic heart disease of native coronary artery
Conditions
Interventions
Intervention 1: Intervention group: tablets containing 500 mg of hydroalcoholic extract of rose hip prepared in the pharmacognosy and pharmaceutical laboratory of Mashhad Faculty of Pharmacy, 2 table
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Diagnosis of Chronic Stable Angina Based on Clinical and Laboratory Parameters Obtaining Informed Consent from the Patient or Patient's Companion Absence of contraindications for exercise testing
Exclusion criteria
Exclusion criteria: Conditions that may compromise the electrocardiogram (ECG) or exercise test interpretation Congestive heart failure functional class III or IV History of acute coronary syndrome Any method of coronary revascularization within two months of enrollment Pregnancy or breastfeeding Renal insufficiency (GFR < 60 ml/min) Liver failure (child pugh score B or C)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total duration of exercise test capacity. Timepoint: At baseline and two months after intervention. Method of measurement: Exercise test system.;Time to onset of angina. Timepoint: At baseline and two months after intervention. Method of measurement: Exercise test system.;Electrocardiographic changes. Timepoint: At baseline and two months after intervention. Method of measurement: Exercise test system.;Double product. Timepoint: At baseline and two months after intervention. Method of measurement: Exercise test system.;Duke score. Timepoint: At baseline and two months after intervention. Method of measurement: Exercise test system. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: At baseline and two months after intervention. Method of measurement: Manometer.;Heart rate. Timepoint: At baseline and two months after intervention. Method of measurement: Exercise test system.;Lipid profile. Timepoint: At baseline and two months after intervention. Method of measurement: Blood test.;Complete blood count(CBC). Timepoint: At baseline and two months after intervention. Method of measurement: Blood test.;Fasting blood sugar. Timepoint: At baseline and two months after intervention. Method of measurement: Blood test.;Liver function test. Timepoint: At baseline and two months after intervention. Method of measurement: Blood test.;Kidney function profile. Timepoint: At baseline and two months after intervention. Method of measurement: Blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir Hooshang Mohammadpour
Mashhad University of Medical Sciences
Outcome results
None listed