The effects of BlackBerry (Morus nigra L.) consumption on serum concentration of lipoproteins , APO A1 , APO B and hs – CRP and blood pressure in dyslipidemic patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201205182365N7

Enrollment

Registered

2012-06-04

Start date

2012-04-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dislipidemia. Hyperlipidaemia, unspecified

Interventions

Black berry , 300 gr , once a day for 8 weeks.

Black berry , 300 gr , once a day for 8 weeks

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: inclusion criteria: informed consent; dislipidemia ( cholesterol > 200 mg/dl and LDL > 100 mg/dl );BMI between 20-35;age between 18-65; no consumption of any drugs affecting lipid metabolism; no consumption of antioxidant supplements of at least one month prior to study entry and during study lack of any systematic disease,inflammation ,choronic or liver and kidney disease;no pregnancy or lactation;no smoking and use of alcoholic beverages;lack of sensivity to the blackberry. Exclusion criteria: not wanting Collaboration; changes in food pattern ; systematic or choronic disease during the study; LDL higher than 160 mg/dl and necessity to medication under specialist.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Total cholesterol. Timepoint: Before and after intervention. Method of measurement: Colorimetric.;LDL-cholesterol. Timepoint: Before and after intervention. Method of measurement: Colorimetric.;HDL-cholesterol. Timepoint: Before and after intervention. Method of measurement: Colorimetric.;TG. Timepoint: Before and after intervention. Method of measurement: Colorimetric.;APO A1. Timepoint: Before and after intervention. Method of measurement: turbidimetry.;APO B. Timepoint: Before and after intervention. Method of measurement: turbidimetry.;Hs-CRP. Timepoint: Before and after intervention. Method of measurement: ELISA.;Systolic blood pressure. Timepoint: Before and after intervention. Method of measurement: Mercury barometer.;Diastolic blood pressure. Timepoint: Before and after intervention. Method of measurement: Mercury barometer.	—

Measure

Time frame

Total cholesterol. Timepoint: Before and after intervention. Method of measurement: Colorimetric.;LDL-cholesterol. Timepoint: Before and after intervention. Method of measurement: Colorimetric.;HDL-cholesterol. Timepoint: Before and after intervention. Method of measurement: Colorimetric.;TG. Timepoint: Before and after intervention. Method of measurement: Colorimetric.;APO A1. Timepoint: Before and after intervention. Method of measurement: turbidimetry.;APO B. Timepoint: Before and after intervention. Method of measurement: turbidimetry.;Hs-CRP. Timepoint: Before and after intervention. Method of measurement: ELISA.;Systolic blood pressure. Timepoint: Before and after intervention. Method of measurement: Mercury barometer.;Diastolic blood pressure. Timepoint: Before and after intervention. Method of measurement: Mercury barometer.

—

Secondary

Measure	Time frame
Weight. Timepoint: Before and after intervention. Method of measurement: scale.;Height. Timepoint: Before and after intervention. Method of measurement: meter.;BMI. Timepoint: Before and after intervention. Method of measurement: mathematics.;Waist circumference. Timepoint: Before and after intervention. Method of measurement: meter.;Energy intake. Timepoint: Before and after intervention. Method of measurement: recall.;Protein intake. Timepoint: Before and after intervention. Method of measurement: recall.;Carbohydrate intake. Timepoint: Before and after intervention. Method of measurement: recall.;Fat intake. Timepoint: Before and after intervention. Method of measurement: recall.;Cholesterol intake. Timepoint: Before and after intervention. Method of measurement: recall.;Fiber intake. Timepoint: Before and after intervention. Method of measurement: recall.;Vitamin A. Timepoint: Before and after intervention. Method of measurement: recall.;Vitamin C. Timepoint: Before and after intervention. Method of measurement: recall.;Vitamin E. Timepoint: Before and after intervention. Method of measurement: recall.;Sodium. Timepoint: Before and after intervention. Method of measurement: recall.;Potasium. Timepoint: Before and after intervention. Method of measurement: recall.;Fruit and vegetables intake. Timepoint: Before and after intervention. Method of measurement: recall.;Level of physical activity. Timepoint: Before and after intervention. Method of measurement: Questionnaire.	—

Measure

Time frame

Weight. Timepoint: Before and after intervention. Method of measurement: scale.;Height. Timepoint: Before and after intervention. Method of measurement: meter.;BMI. Timepoint: Before and after intervention. Method of measurement: mathematics.;Waist circumference. Timepoint: Before and after intervention. Method of measurement: meter.;Energy intake. Timepoint: Before and after intervention. Method of measurement: recall.;Protein intake. Timepoint: Before and after intervention. Method of measurement: recall.;Carbohydrate intake. Timepoint: Before and after intervention. Method of measurement: recall.;Fat intake. Timepoint: Before and after intervention. Method of measurement: recall.;Cholesterol intake. Timepoint: Before and after intervention. Method of measurement: recall.;Fiber intake. Timepoint: Before and after intervention. Method of measurement: recall.;Vitamin A. Timepoint: Before and after intervention. Method of measurement: recall.;Vitamin C. Timepoint: Before and after intervention. Method of measurement: recall.;Vitamin E. Timepoint: Before and after intervention. Method of measurement: recall.;Sodium. Timepoint: Before and after intervention. Method of measurement: recall.;Potasium. Timepoint: Before and after intervention. Method of measurement: recall.;Fruit and vegetables intake. Timepoint: Before and after intervention. Method of measurement: recall.;Level of physical activity. Timepoint: Before and after intervention. Method of measurement: Questionnaire.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Reza Vafa

Tehran University of Medical Sciences

rezavafa@yahoo.com+98 21 8877 9118

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026