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Effect of intracoronary adenosine injection before stenting in emergency primary percutaneous coronary intervention for preventing no-reflow phenomenon in patients with ST elevation myocardial infarction

Effect of intracoronary adenosine injection before stenting in emergency primary percutaneous coronary intervention for preventing no-reflow phenomenon in patients with ST elevation myocardial infarction

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120516009768N6
Enrollment
220
Registered
2019-07-21
Start date
2019-03-01
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ST segment elevation myocardial infarction. ST elevation (STEMI) myocardial infarction of unspecified site

Interventions

Intervention 1: Intervention group: ?Will receive intracoronary adenosine infusion (200 mcg bolus for right-side coronary arteries and 400 mcg bolus for the left-side coronary arteries) through the gu

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Diagnosis of ST-elevation myocardial infarction based on electrocardiogram and laboratory test Consent for taking part in the study TIMI flow frade=0-1 in the coronary angiography Having the criteria for primary percutaneous coronary intervention

Exclusion criteria

Exclusion criteria: Cardiogenic shock Complete AV block Chronic Renal Failure (Serum creatinine >3 mg/dl) Need for emergency coronary artery bypass graft surgery

Design outcomes

Primary

MeasureTime frame
No reflow phenomenon is the failure of blood to reperfuse an ischemic area after revascularization. Timepoint: After stenting. Method of measurement: Based on the angiographic tools: TIMI flow grade, TIMI frame count & Myocardial blush grade.—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAkbar Shafiee

Tehran University of Medical Sciences

dr_shafiee@alborzi.com+98 21 8802 9600

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026