schizophrenia. schizophrenia
Conditions
Interventions
Treatment - Drugs
Placebo
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Postmenopausal women, Diagnosis of Schizophrenia based on DSM IV , chronic Schizophrenia( duration of the disorder>2 years), Minimum Score of 20 on Negative subscale Exclusion Criteria: Substance dependence( except for nicotine and cafeine), IQ <70, any other mental disorder on axis I, Any serious medical or neurological problem , receiving oral antipsychotic medications during the last week or receiving any depot antipsychotic medication during the last month, receiving ECT during the last 14 days,hepatic and renal disease , Endocrine abnormality, history of thrombosis and emboli, history of abnormal uterine bleeding, uterine or breast cancer, history of CVA, Hormone replacement therapy
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of schizophrenia. Timepoint: Baseline and weeks 2-4-6-8 after beginig of treatment. Method of measurement: Positive and Negative Syndrome Scale (PANSS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactProf. Shahin Akhondzadeh
Tehran University of Medical Sciences
Outcome results
None listed