Acute Kidney Injury. Acute renal failure
Conditions
Interventions
Intervention 1: Intervention group: Intravenous lasix 40-80mg and then maintenance dose of 1-5 mg/h for 7 days. Intervention 2: Control group:standard treatment with placebo for 7 days.
Treatment - Drugs
Intervention group: Intravenous lasix 40-80mg and then maintenance dose of 1-5 mg/h for 7 days
Control group:standard treatment with placebo for 7 days
Sponsors
Tabriz University of medical sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients with Acute Kidney Injury; creatinine rise more than 150-300%, or urine output less than 0.5 cc/kg/h for less than 12 hours Exclusion criteria: previous history of acute kidney injury; dialysis; renal transplantation; urinary tract obstruction; hypovolemia
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acute Kidney Injury. Timepoint: First, third and seventh day. Method of measurement: Blood Urea Nitrogen?Urea, Urine Output. | — |
Secondary
| Measure | Time frame |
|---|---|
| N-GAL. Timepoint: First, Third and Seventh day. Method of measurement: N-GAL will be measured using USCnlife kit. Blood samples will be taken from the patients and immediately placed in a centrifuge with a round of 3000/min for15 minutes, then poured into the microtube and with maintaining the cold chain, transferred to the - 80 ° C freezer until the time of NGAL assessing. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAta Mahmoodpoor
Tabriz University of Medical Sciences
Outcome results
None listed