Effect of vitamin c supplement on anemia in peritoneal dialysis patients

Randomized, double blind, placebo controlled Trial of effect of vitamin c supplement on anemia in peritoneal dialysis patients in Imam Reza center - Shiraz

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201205089674N1

Enrollment

Registered

2014-01-01

Start date

2012-02-11

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anemia. Scorbutic Anemia

Interventions

Intervention 1: Group A,(consist of 22 person)- vitamin C supplement orally up to 250 mg per day for 6 weeks was prescribed. Plasma levels of vitamin C and other clinical parameters including hemoglob

Treatment - Drugs

Placebo

Group A,(consist of 22 person)- vitamin C supplement orally up to 250 mg per day for 6 weeks was prescribed. Plasma levels of vitamin C and other clinical parameters including hemoglobin, ferritin, TI

Placebo prescribed to Group B. Plasma levels of vitamin C and other clinical parameters including hemoglobin, ferritin, TIBC, iron and CRP were measured at the beginning and end of the study.

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. Long-term treatment of PD (at least more than three months) 2. Hemoglobin less than 11 milligrams per liter 3. Age over 18 years - Exclusion criteria of the study: 1. Acute illness (including infectious diseases and cancer) within 3 months prior to determining the level of vitamin C 2. Any recent blood transfusion, recurrent bleeding or hemolysis 3. Supplementation with vitamin C during the 3 weeks prior to the determination of serum levels 4. Consumption of tetracycline, antacid and Cholestyramine

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Hemoglobin. Timepoint: Before and 6 weeks after intervention. Method of measurement: Lab Method.;Vit C Level. Timepoint: Before and 6 weeks after intervention. Method of measurement: HPLC.	—

Secondary

Measure	Time frame
C Reactive Protein. Timepoint: Before and 6 week after intervention. Method of measurement: Lab Method.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Zahra Lotfi

Shiraz University of Medical Sciences

zah_lotfi@yahoo.com; lotfi.farideh@gmail.com+98 71 1647 4316

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026