The effect of Mg on the cardiac biomarker proBNP

The effect of magnesium sulfate infusion on blood levels of ProBNP in patients undergoing coronary artery bypass grafting

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201205069650N1

Enrollment

Registered

2012-06-28

Start date

2012-06-30

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atherosclerotic heart disease. Atherosclerotic heart disease

Interventions

Intervention 1: Control: infusion of Normal Saline. Intervention 2: Intervention: MgSO4 infusion 20mg/kg/hour.

Placebo

Treatment - Drugs

Control: infusion of Normal Saline

Intervention: MgSO4 infusion 20mg/kg/hour

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: significant coronary artery stenosis (2VD or 3VD) and EF1.8; 5.Emergent surgery; 6.Unstable angina; 7.Redo surgery; 8.Combination surgery (carotid endarterectomy, vulvoplasty); 9.long QT syndrome, neuromuscular junction disorders.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
ProBNP. Timepoint: before intervention, 24 hours after intervention. Method of measurement: ELISA based lab kit.	—

Secondary

Measure	Time frame
Mechanical ventilation time. Timepoint: days on mechanical ventilation. Method of measurement: questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mahnoosh Foroughi

Shahid Beheshtil Universityof Medical Sciences

mahnoosh.foroughi@gmail.com+98 21 2208 3106

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026