Effect of Acetaminophen and Fentanyl on pain after urologic surgeries

The effect of intravenous Acetaminophen and Fentanyl on post operative pain after urologic surgeries: a single blinded randomized controlled trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201204309597N1

Enrollment

Registered

2013-06-03

Start date

2013-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Lower abdominal pain. Condition 2: Pelvic and perineal pain. Pain localized to other parts of lower abdomen Pelvic and perineal pain

Interventions

Intervention 1: 40 patients will receive a single dose of 1000 mg intravenous Acetaminophen (paracetamol) during the last 15 minutes of surgery. Intervention 2: 40 patients will receive a single dose

Treatment - Drugs

40 patients will receive a single dose of 1000 mg intravenous Acetaminophen (paracetamol) during the last 15 minutes of surgery

40 patients will receive a single dose of 2 mgr/kg intravenous Fentanyl during the last 15 minutes of surgery.

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: (a) patients with class 1 or 2 according to the American Society of Anesthesiology scoring criteria; (b) age of 18-65 years. Exclusion criteria: (a) history of hepatic or renal diseases; (b) history of psychotropic or opium drugs consumption; (c) sensitivity to Acetaminophen; (d) any contraindication to spinal anesthesia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain severity. Timepoint: 1, 6, 12, 18, and 24 hours after surgery. Method of measurement: Visual Analog Scale (VAS).;Opium dose (mg) usage. Timepoint: 1, 6, 12, 18, and 24 hours after surgery. Method of measurement: Medical record.;Hemodynamic status (blood pressure, heart rate). Timepoint: 1, 6, 12, 18, and 24 hours after surgery. Method of measurement: Physical examination.	—

Secondary

Measure	Time frame
Nausea. Timepoint: 2 hours after surgery. Method of measurement: Questionnaire.;Vomiting. Timepoint: 2 hours after surgery. Method of measurement: Questionnaire.;Urinary retention. Timepoint: 12 hours after surgery. Method of measurement: Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Mohammad Zolhavarieh

Hamadan University of Medical Sciences

dsmbszolhavarieh@yahoo.com+98 81 1838 0749

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026