Femoral shaft fracture. Fracture of shaft of femur
Conditions
Interventions
Intervention 1: In this Clinical Trail perineural administration of dexmedetomidine, 100 µg, was done before anesthesia. Intervention 2: In the control group anesthesia was done without perineural adm
Treatment - Drugs
Treatment - Surgery
In this Clinical Trail perineural administration of dexmedetomidine, 100 µg, was done before anesthesia.
In the control group anesthesia was done without perineural administration of dexmedetomidine and surgery was done.
Sponsors
anesthesiology research centre,shahid beheshti university of medical sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Exclusion criteria: allergy to an a2-adrenergic agonist or to one of the drugs used during the study; atracurium; propofol; morphine; midazolam; dexmedetomidine; lidocaine and fentanyl; age <18 years, renal and hepatic failure; planned intraoperative use of regional analgesia; addicted patients, treatment or consumption psychotropic medication or an opioid agonist or antagonist in the 24 hours before surgery; treatment with a2-adrenergic agonist or antagonist; ASA physical status III–IV patients; and patient less or more than 40 and 100 kg weight, respectively. Inclusion criteria: all patients with an elective femoral shaft fracture who had not exclusion criteria and their surgery duration was less than 3 hours were included in the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Propofol consumption. Timepoint: during 3 hour intraoparative. Method of measurement: propofol consumption.;Pain intensity. Timepoint: during 3 hour intraoparative and 6, 12, and 24 hour postoperative. Method of measurement: visual measurment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Narcotic consumption. Timepoint: 1, 2 and 3 hours intra-operative and 24 hour postoperative. Method of measurement: consumpted drug. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactElham Memari
Shahid Beheshti University of Medical Sciences
Outcome results
None listed