Skip to content

Effect of misoprostol in Cervical ripening

Comparison of vaginal misoprostol with oral misoprostol in cervical priming before hystroscopic surgery in postmenopausal women and perimenopausal women without history of Normal Vaginal Delivery.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201204308588N6
Enrollment
120
Registered
2012-06-14
Start date
2012-06-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

operative Hystroscopic Surgery.

Interventions

Intervention 1: 400 micro gram Vaginal misoprostol 10-12 hours before surgery. Intervention 2: 400 Microgram sublingual 10-12 hours before surgery. Intervention 3: No intervention.
Treatment - Drugs
400 micro gram Vaginal misoprostol 10-12 hours before surgery
400 Microgram sublingual 10-12 hours before surgery.
No intervention

Sponsors

Tehran University of Medical Sciences.
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
40 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria:menopausal women and perimenopausal women without history of normal vaginal delivery;who are not pregnant at the time of examination; do not have contraindications for prostaglandins(severe asthma, glaucoma, cardiac disease, hypertension or renal failure); do not have severe uterovaginal prolapse; do not have history of cervical surgery or cervical incompetency.Exclusion criteria: history of normal vaginal delivery in perimenopausal women;pregnancy; have contraindications for prostaglandins(severe asthma, glaucoma, cardiac disease, hypertension or renal failure); have severe uterovaginal prolapse;have history of cervical surgery or cervical incompetency.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Cervical Width. Timepoint: 10-12 hours after intervention. Method of measurement: by surgeon during operation.

Secondary

MeasureTime frame
Time of Dilatation. Timepoint: 10-12 hours after Intervention. Method of measurement: By surgeon during operation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Mahboobeh Saberi

Hazret Rasool-e- Akram Hospital

mmsminoo@gmail.com+98 21 6435 2434

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026