Effect of intravenous Dexmedetomidine and Dexamethasone on spinal anesthesia in opium addicted patients

Comparison between intravenous Dexamethasone and Dexmedtomidine on spinal anesthesia level in opium addicted patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120430009593N15

Enrollment

Registered

2021-12-01

Start date

2021-12-21

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dexmedetomidine and Dexamethasone on Spinal Anesthesia Level in Opium Addicted Patients.

Interventions

Intervention 1: Control group : Dexamethasone 8 mg 10 minutes before spinal anesthesia with bupivacaine and then normal saline infusion at a rate of 0.5 µg / kg / hr during surgery. Each Dexamesthaso

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with drug addiction Patients with ASA class 1,2 Patients with BMI <30 Patients aged 18 to 65 years

Exclusion criteria

Exclusion criteria: Pregnant patients Patients with dissatisfaction with spinal anesthesia Patients with coagulation disorders Patients with a history of multiple sclerosis Patients with local infection in the lumbar region Patients with allergies to local anesthetics Patients with systemic infections Patients with diabetic neuropathy Patients with bradycardia with less than 50 HR

Design outcomes

Primary

Measure	Time frame
Onset of Sensory Block. Timepoint: Every 3 Minutes to 15 Minutes and then Every 5 Minutes to 30 Minutes and Every 15 Minutes to 2 Hours. Method of measurement: Pinprick Test.;Onset of Motor Block. Timepoint: Every 3 Minutes to 15 Minutes and then Every 5 Minutes to 30 Minutes and Every 15 Minutes to 2 Hours. Method of measurement: Bromage Scale.;Duration of Motor Block. Timepoint: Every 3 Minutes to 15 Minutes and then Every 5 Minutes to 30 Minutes and Every 15 Every to 2 Hours. Method of measurement: Bromage Scale.;Regression of Two Level of Sensory Block. Timepoint: Every 3 Minutes to 15 Minutes and then Every 5 Minutes to 30 Minutes and Every 15 Minutes to 2 hours. Method of measurement: Pinprick Test.	—

Measure

Time frame

Onset of Sensory Block. Timepoint: Every 3 Minutes to 15 Minutes and then Every 5 Minutes to 30 Minutes and Every 15 Minutes to 2 Hours. Method of measurement: Pinprick Test.;Onset of Motor Block. Timepoint: Every 3 Minutes to 15 Minutes and then Every 5 Minutes to 30 Minutes and Every 15 Minutes to 2 Hours. Method of measurement: Bromage Scale.;Duration of Motor Block. Timepoint: Every 3 Minutes to 15 Minutes and then Every 5 Minutes to 30 Minutes and Every 15 Every to 2 Hours. Method of measurement: Bromage Scale.;Regression of Two Level of Sensory Block. Timepoint: Every 3 Minutes to 15 Minutes and then Every 5 Minutes to 30 Minutes and Every 15 Minutes to 2 hours. Method of measurement: Pinprick Test.

—

Secondary

Measure	Time frame
Total Analgesia Time. Timepoint: Every 3 Minutes to 15 Minutes and then Every 5 Minutes to 30 Minutes and Every 15 Minutes to 2 Hours. Method of measurement: ??According to Time with Visual Analogue Scale less than 3.;The First Time for Analgesia Requirement. Timepoint: Every 3 Minutes to 15 Minutes and then Every 5 Minutes to 30 Minutes and Every 15 Minutes to 2 Hours. Method of measurement: Analgesic Request According to VAS More than 3.	—

Measure

Time frame

Total Analgesia Time. Timepoint: Every 3 Minutes to 15 Minutes and then Every 5 Minutes to 30 Minutes and Every 15 Minutes to 2 Hours. Method of measurement: ??According to Time with Visual Analogue Scale less than 3.;The First Time for Analgesia Requirement. Timepoint: Every 3 Minutes to 15 Minutes and then Every 5 Minutes to 30 Minutes and Every 15 Minutes to 2 Hours. Method of measurement: Analgesic Request According to VAS More than 3.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Memary

Shahid Beheshti University of Medical Sciences

drmemary@sbmu.ac.ir00982173430

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026