Skip to content

Determination of oxytocin dose based on “rule of threes” algorithm and Williams guideline in the elective cesarean delivery

Evaluation and comparison of administrated oxytocin dose based on “rule of threes” algorithm with Williams guideline in the elective cesarean delivery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120430009593N13
Enrollment
110
Registered
2020-03-09
Start date
2016-09-22
Completion date
Unknown
Last updated
2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elective cesarean delivery. Encounter for cesarean delivery without indication

Interventions

Intervention 1: Intervention group:The patients in “rule of threes” algorithm group received Bolus oxytocin 3IU/3ml (0.9% saline) . At 3 and 6 min, an “inadequate” uterine tone assessment resulted in

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: The women who undergoing to the first to third elective Cesarean delivery with spinal anesthetic technique American Society of Anesthesiologists (ASA) physical status I–II

Exclusion criteria

Exclusion criteria: Labor pain The presence of maternal risk factors for uterine atony The presence of fetal risk factors for uterine atony Diabetes melitus Thrombocytopenia<100000 per microliter Uterine fibroma

Design outcomes

Primary

MeasureTime frame
Creating of adequate uterine tonicity. Timepoint: at 3, 6, 9, 12, and 15 min after onset of surgery. Method of measurement: Uterine tonicity was evaluated as atonic, partial tonicity, adequate tonicity, well contracted and very well contracted by obstetrician.

Secondary

MeasureTime frame
The time of administrated oxytocin to obtain adequate tonicity. Timepoint: At 3, 6, 9, 12, and 15 minute after onset of cesarean. Method of measurement: The mean administrated oxytocin.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Memari

Shahid Beheshti University of Medical Sciences

drmemary@gmail.com+98 77557840

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026