Determination of ED90 of oxytocin to obtain adequate uterine tonicity during cesarean section in high and low-risk patients

Determination and Comparison of ED90 of prophylactic oxytocin after placental removal during cesarean section in patients with high and low risk for postpartum uterine atony

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120430009593N11

Enrollment

Registered

2020-02-10

Start date

2019-11-22

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postpartm atonia after cesarian section.

Interventions

Intervention 1: the control group included low-risk pregnant women for atony. who will be received oxytocin based on rule of three algorithm to obtain adequate uterine tonicity and estimate the ED90(

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Age 18 to 38 year-old ASA I and II The pregnant women candidate for cesarean

Exclusion criteria

Exclusion criteria: Any condition led to change spinal anesthesia to general anesthesia History of sensitivity to oxytocin History of hemorrhagic disorders ASA III and IV

Design outcomes

Primary

Measure	Time frame
Achieving an effective dose of oxytocin in 90% of low-risk and high-risk cesarean candidates. Timepoint: After delivery of the placenta and during cesarean delivery at 0, 3, 6, 9, 15, 30 minutes during cesarean, end of surgery and recovery of patients. Method of measurement: Measurement of oxytocin administrated.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamira Abaspour

Shahid Beheshti University of Medical Sciences

dr.abbaspour1394@gmail.com+98 21 7756 7840

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026