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Effect of mouthwash on gingival disease

Comparative evaluation of salivary substantivity and antiplaque efficacy of mouthwashes containing chlorhexidine, cetylpyridinium chloride and Salvarora Persica in gingivitis patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201204289582N1
Enrollment
16
Registered
2013-12-02
Start date
2012-12-06
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

prevention of periodontal diseases. Gingivitis and periodontal disease

Interventions

Intervention 1: Group 1: First part: Salivary substantivity of mouthwashes: 1- 0.12% local Chlorhexidine mouthwash, once 10cc for 30 Sec. 2- Persica mouthwash, once 10cc for 30 Sec. 3- 0.12% Chlorhe
Treatment - Drugs
Diagnosis
Group 1: First part: Salivary substantivity of mouthwashes: 1- 0.12% local Chlorhexidine mouthwash, once 10cc for 30 Sec. 2- Persica mouthwash, once 10cc for 30 Sec. 3- 0.12% Chlorhexidine Kin Gi
Group 2: First part: Salivary substantivity of mouthwashes: 1- Normal saline, once 10cc for 30 Sec. 2- 0.12% local Chlorhexidine mouthwash, once 10cc for 30 Sec. 3- Persica mouthwash, once 10cc fo
Group 3: First part: Salivary substantivity of mouthwashes: 1- Persica mouthwash, once 10cc for 30 Sec. 2- 0.12% Chlorhexidine Kin Gingival( Spain, once 10cc for 30 Sec. 3- CPC (Oral-B), once 10c
Group 4: First part: Salivary substantivity of mouthwashes: 1- 0.12% Chlorhexidine Kin Gingival (Spain) once 10cc for 30 Sec. 2- CPC (Oral-B) mouthwash, once 10cc for 30 Sec., 3- 0.2% local Chlor
Group 5: First part: Salivary substantivity of mouthwashes: 1- CPC (Oral-B) mouthwash, once 10cc for 30 Sec., . 2- 0.2% local Chlorhexidine mouthwash, once 10cc for 30 Sec. 3- Normal saline, once 1
Group 6: First part: Salivary substantivity of mouthwashes: 1- 0.2% local chlorhexidine mouthwash, once 10cc for 30 Sec. 2- Normal saline, once 10cc for 30 Sec. 3- 0.12% local Chlorhexidine mouthw

Sponsors

Dental School, Tehran Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria; 18 years and above; minimum of 24 teeth; no partial or fixed prosthesis and not under orthodontic treatment; no gingival sulcus deeper than 3mm; maximum plaque index( Turesky et al) of 2 and gingival index( Loa and Silness) of 1.5 Exclusion criteria: Age above 45 years, not smoker; no antibiotic therapy or routine antiseptic use for past 3 months; allergy to any mouth washes; no patient compliance

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Number of vital bacteria. Timepoint: before and after 30 second; 1; 3; 5 and 7 hours of single use of 10cc of mouthwash for 45 seconds. Method of measurement: Epiflourescence.;Bacterial Plaque. Timepoint: 4 days after use. Method of measurement: Turesky Plaque Index.

Secondary

MeasureTime frame
Change in taste sensation. Timepoint: 4 days. Method of measurement: Visual Analog Scale.;Burning sensation. Timepoint: 4 days. Method of measurement: Visual analog Scale.;Presence of stain. Timepoint: 4 days. Method of measurement: Observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahmood Ghasemi

Dentla school, Tehran Islamic Azad University

m_ghasemi@dentaliau.ac.ir+98 21 2256 4571

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026