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A Comparative Study of Granisetron and Ondansetron and petedin for Prevention of Postoperative Shivering: A Randomized Clinical Trial

A Comparative Study of Granisetron and Ondansetron and petedin for Prevention of Postoperative Shivering: A Randomized Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201204284093N4
Enrollment
120
Registered
2012-05-25
Start date
2012-09-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

shivering. Other specified general symptoms and signs

Interventions

Intervention 1: Granisetron(40?g//kg, increased volume to 2 ml) before induction of anesthesia. Intervention 2: Ondansetron(4mg, increased volume to 2 ml) before induction of anesthesia. Intervention
Prevention
Granisetron(40?g//kg, increased volume to 2 ml) before induction of anesthesia
Pethidine (25 mg, inceased volume to 2 ml) before induction of anesthesia

Sponsors

Ardabil University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Candidate for surgery (General, Orthopedic and ENT surgeries), general anesthesia, ASA class I-II Exclusion criteria: history of substance abuse, presence of neuromuscular diseases, hypersensitivity to the study drugs, evidence of grade 3 or 4 of heart failure, fever (more than 37/8 ° orally), history of alpha2-receptor antagonist drugs consumption

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Postoperative shivering. Timepoint: After surgery in recovery room. Method of measurement: Visual analog scale of chills.

Secondary

MeasureTime frame
Central and peripheral temperature. Timepoint: Before the intervention, during surgery, in the recovery room after surgery. Method of measurement: Tympanic and environmental Thermometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Masood Entezariasl

Ardabil University of Medical Sciences

m.entezari@arums.ac.ir+98 45 1772 3010

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026