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comparative evaluation of the effect of misoprostol vaginal suppository to vaginal misoprostol with nitroglycerine in rippening of cervix in term pregnancy reffered to kowsar hospital

comparative evaluation of the effect of vaginal misoprostol to vaginal misoprostol with nitroglycerine in cervix rippening in pregnant women at term referred to Kowsar hospital of Qazvin province

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120428009576N4
Enrollment
106
Registered
2020-02-03
Start date
2018-06-22
Completion date
Unknown
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ripening cervix.

Interventions

Intervention 1: First intervention group: In the dual drug group, misoprostol is given at a dose of 25 micro grams vaginal with nitroglycerin 40 mg vaginal and after 6 hours, the cervix is examined f

Sponsors

Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Primigravida Gestational age>=37 week Bishop score5 Singleton

Exclusion criteria

Exclusion criteria: Surgery on the uteus or previous cesarean section chronic hypertension and preeclampsia uterine contractions The presence of heart, kidney and liver disease rapture of membrane IUGR Suspected embryonic anomalies chorioamnionitis Fever above 38 ° C polyhydramnios Pre-delivery hemorrhage fetal distress

Design outcomes

Primary

MeasureTime frame
The duration of cervical ripening until delivery. Timepoint: 6 and 12 hours. Method of measurement: Vaginal exam.

Secondary

MeasureTime frame
Duration of taking the drug until the onset of the active phase of labor. Timepoint: every 2 hours. Method of measurement: Vaginal exam.;Duration of taking drug until delivery. Timepoint: every 2 hours. Method of measurement: Vaginal exam.;Duration of the fist phase of labor. Timepoint: every 2 hours. Method of measurement: Vaginal exam.;Duration of the second phase of labor. Timepoint: every 1 hours. Method of measurement: Vaginal exam.;Reach to vaginal delivery. Timepoint: After delivery. Method of measurement: Date sheet.;Type of delivery. Timepoint: After delivery. Method of measurement: Date sheet.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Rafiee

Qazvin University of Medical Sciences

dr_seidjavadi@yahoo.com+98 28 3333 6001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026