Third molar extraction. An impacted tooth is a tooth that has failed to erupt because of obstruction by another tooth
Conditions
Interventions
Administration of 400 mg ibuprofen tablet before usual third molar extraction by a surgeon.
Treatment - Drugs
Administration of 400 mg ibuprofen tablet before usual third molar extraction by a surgeon
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria 1. have impacted third molar in lower jaw (one or two side) 2. Having teeth needed partial removal of bone for extraction 3. Lack of history of GI disease and peptic ulcer 4. Lack of systemic diseases such as diabetes, chronic renal failure, chronic hepatic impairment, ... 5. Lack of hypersensitivity to aspirin or related compounds 6. Lack of use of drugs that interfere with analgesic effects of NSAIDs. Exclusion criteria: 1- Active infection immediately before or after surgery. 2- Use of other analgesics within 8 hours of surgery. 3- History of gastric ulcers or erosion. 4-history of anti coagulation therapy 5- History of asthma, nasal polyps, and allergic disorders associated with aspirin and other NSAID. 6- Uncontrolled systemic diseases 7- Female patients who were pregnant or who were not using an accepted from of birth control.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity. Timepoint: Within 24 hrs of surgery with 2 hrs time intervals. Method of measurement: VAS. | — |
Secondary
| Measure | Time frame |
|---|---|
| Total analgesic consumption and time to first analgesic use. Timepoint: Within 24 hrs after the surgery. Method of measurement: Self report. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Masoumeh Emamghoreishi
Shiraz University of Medical Sciences- Medical School
Outcome results
None listed