chronic constipation. Constipation
Conditions
Interventions
Intervention 1: Treatment with polyethylene glycol 0.6 gram/Kg/day two times a day for 6 months and motilium syrup 0.15 mg/Kg/dose three times a day for 3 months (1 mL=1 mg Syrup). Intervention 2: Tre
Treatment - Drugs
Placebo
Treatment with polyethylene glycol 0.6 gram/Kg/day two times a day for 6 months and motilium syrup 0.15 mg/Kg/dose three times a day for 3 months (1 mL=1 mg Syrup)
Treatment with polyethylene glycol 0.6 gram/Kg/day two times a day for 6 months and placebo syrup 0.15 mL/Kg/dose three times a day for 3 months
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Years to 18 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Having Rome III criteria for definition of functional constipation. Two or more of the following in a child with a developmental age of at least 4 years with insufficient criteria for diagnosis of inflammatory bowel syndrome: Two or fewer defecations in the toilet per week; At least 1 episode of fecal incontinence per week; history of retentive posturing or excessive volitional stool retention; History of painful or hard bowel movements; Presence of a large fecal mass in the rectum; History of large diameter stools Criteria fulfilled at least once per week for at least 2 months before diagnosis, and one month of at least two of the following in infants up to 4 years of age: Two or fewer defecations per week; At least one episode/week of incontinence after the acquisition of toileting skills; History of excessive stool retention; History of painful or hard bowel movements ; Presence of a large fecal mass in the rectum; History of large diameter stools. The exclusion criteria: constipation due to any organic causes such as Hirschsprung disease, hypothyroidism, anal stenosis or use of medications that cause constipation.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Constipation. Timepoint: before intervention, one month and three months after intervention, and three months after the end of intervention. Method of measurement: Rome III criteria. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Mohsen Dehghani
Shiraz University of Medical Sciences
Outcome results
None listed