Assessment of the efficacy of using intraumbilical vein injection of oxytocin after delivery of newborn in reducing postpartum hemorrhage

Assessment of the efficacy of using intraumbilical vein injection of oxytocin in active management of the third stage of labor

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201204179491N1

Enrollment

200

Registered

2012-05-04

Start date

2011-12-28

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postpartum hemorrhage. Third-stage haemorrhage

Interventions

Intervention 1: Intervention group: in the third stage of labor,after clamping of umbilicus,10 international units of oxytocin diluted in 9 mililiter of ringer was injected in intraumbilical vein(p

Treatment - Drugs

Intervention group: in the third stage of labor,after clamping of umbilicus,10 international units of oxytocin diluted in 9 mililiter of ringer was injected in intraumbilical vein(proximal to the

Control group:in the third stage of labor,after clamping of the umbilicus,10 milliliter of ringer was injected intraumbilical vein and 10 international units of oxytocin diluted in 9 milliliter of rin

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria : vaginal delivery;gestational age 37-42 weeks;singleton pregnancy;live fetus;cephalic presentation;neonatal birth weight 2500-4500 gram;parity 1-3. exclusion criteria : blood pressure140/90 or greater;placenta previa;placental abruption;abnormal placentation;instrumental delivery;history of postpartum hemorrhage; history of curretage or cesarean delivery or any uterine scar;coagulopathy;hydramnios;known uterine anomaly;large episiotomy or vaginal lacerations those were repaired in operation room.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Assessment of the efficacy of using intraumbilical vein injection of oxytocin in active management of the third stage of labor in reducing postpartum hemorrhage. Timepoint: 24 hours after intervention. Method of measurement: hemoglobin level(gr/dl).	—

Secondary

Measure	Time frame
Incidence of retained placenta need for manual removal of placenta in each group. Timepoint: in third stage of labor. Method of measurement: percentage.;Incidence of using additional uterotonics in each group. Timepoint: during the third stage of labor and 24 hours later. Method of measurement: percentage.;Incidence of falling hemoglobin levels in each group. Timepoint: during the third stage of labor and 24 hours later. Method of measurement: gr/dl.;Duration of the third stage of labor in each group. Timepoint: during the third stage of labor. Method of measurement: minutes and seconds.;Incidence of transfusion after delivery in each group. Timepoint: during 24 hours after delivery. Method of measurement: percentage.	—

Measure

Time frame

Incidence of retained placenta need for manual removal of placenta in each group. Timepoint: in third stage of labor. Method of measurement: percentage.;Incidence of using additional uterotonics in each group. Timepoint: during the third stage of labor and 24 hours later. Method of measurement: percentage.;Incidence of falling hemoglobin levels in each group. Timepoint: during the third stage of labor and 24 hours later. Method of measurement: gr/dl.;Duration of the third stage of labor in each group. Timepoint: during the third stage of labor. Method of measurement: minutes and seconds.;Incidence of transfusion after delivery in each group. Timepoint: during 24 hours after delivery. Method of measurement: percentage.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReyhaneh Ramezaninezhad

Qazvin University of Medical Sciences

rramezaninezhad@qums.ac.irrramezaninejad@yahoo.com+98 28 1223 6374

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026