Type 2 diabetes. Type 2 diabetes mellitus
Conditions
Interventions
Intervention 1: Intervention group (n=45): all patients receive relevant dietary recommendations and are asked not to change their diet and physical activity. Also, the participants of the interventio
Sponsors
Vice-chancellor for research Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
25 Years to 70 Years
Inclusion criteria
Inclusion criteria: Willingness to participate in the study and signing of the consent form Diagnosis of type 2 diabetes (fasting blood sugar higher than or equal to 126mg / dl or two hours above 200mg / dl or random blood sugar above 200 with one of the symptoms of hyperglycemia or hyperlipidemia) At least one year of history of diabetes (diagnosis of diabetes based on a doctor's opinion) Serum triglyceride above 200 mg / dl. Age range 25 to 70 years old Their body mass index is 20-35 Do not take any antioxidant and dietary supplements during the last 2 months Not getting pregnant and breastfeeding Do not have other chronic and inflammatory diseases
Exclusion criteria
Exclusion criteria: Smoking and any Drugs Cardiovascular, renal or liver diseases Use any antioxidant and dietary supplement during the last two months Use of Insulin Alcohol consumption Any allergies (gastrointestinal or skin) to any antioxidant or multivitamin supplement
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting Blood Sugar (FBS). Timepoint: Before intervention and 12 week after intervention. Method of measurement: Calorie meter method.;Fasting insulin. Timepoint: Before intervention and 12 week after intervention. Method of measurement: ELISA.;LDL-C. Timepoint: Before intervention and 12 week after intervention. Method of measurement: Calorie meter method.;HDL-C. Timepoint: Before intervention and 12 week after intervention. Method of measurement: Calorie meter method.;Total triglyceride. Timepoint: Before intervention and 12 week after intervention. Method of measurement: Calorie meter method.;Total cholesterol. Timepoint: Before intervention and 12 week after intervention. Method of measurement: Calorie meter method.;HOMA- Insulin resistance. Timepoint: Before intervention and 12 week after intervention. Method of measurement: Calculation.;Quantitative insulin sensitivity check index (QUICKI). Timepoint: Before intervention and 12 week after intervention. Method of measurement: Calculation.;High sensitivity C-reactive protein. Timepoint: Before intervention and 12 week after intervention. Method of measurement: Immunoturbidimetric method.;Total Antioxidant Capacity. Timepoint: Before intervention and 12 week after intervention. Method of measurement: Calorie meter method.;Superoxide dismutase (SOD). Timepoint: Before intervention and 12 week after intervention. Method of measurement: Calorie meter method.;Glutathione peroxidase (GSH-PX). Timepoint: Before intervention and 12 week after intervention. Method of measurement: Calorie meter method. | — |
Secondary
| Measure | Time frame |
|---|---|
| Micronutrients and Macronutrients intake. Timepoint: Before intervention and 12 week after intervention. Method of measurement: 24 hour recall questionnaire.;Weight. Timepoint: Before intervention and 12 week after intervention. Method of measurement: scales.;Height. Timepoint: Before intervention and 12 week after intervention. Method of measurement: meter.;Waist. Timepoint: Before intervention and 12 week after intervention. Method of measurement: Meter.;Body Mass Index (BMI). Timepoint: Before intervention and 12 week after intervention. Method of measurement: Calculation.;Systolic blood pressure. Timepoint: Before intervention and 12 week after intervention. Method of measurement: Digital barometric.;Diastolic blood pressure. Timepoint: Before intervention and 12 week after intervention. Method of measurement: Digital barometric.;Physical activity. Timepoint: Before intervention and 12 week after intervention. Method of measurement: International Physical Activity Questionnaire (IPAQ).;Total energy intake. Timepoint: Before intervention and 12 week after intervention. Method of measurement: 24 hour recall questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Nahid Aryaeian
Iran University of Medical Sciences
Outcome results
None listed