Polycystic ovary syndrome. Poly cystic ovarian syndrome
Conditions
Interventions
Intervention 1: Control group: Patients referring to Akbar Abadi Hospital who are willing to cooperate and have inclusion criteria will receive 3 gr Starch(3 capsules of 1 gram) for 3 months. Interve
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Patients with polycystic ovary syndrome based on two criteria of the three diagnostic criteria of the disease based on Rotterdam1. Reduction of bleeding or discontinuation (as: Delay more than 35 days or less than 8 bleeding episodes per year); 2. Clinical symptoms including hirsutism or Ferriman-Gallwey (MFG) score above 8,acne and Male pattern baldness, biochemical symptoms of increased endogenesis ,3.polycystic ovary (12 or more of 12 follicles per ovary with diameter of 2 to 9 mm , or an increase in ovarian volume to more than 310 ml) Reduction of bleeding or discontinuation (as: Delay more than 35 days or less than 8 bleeding episodes per year); Clinical symptoms including hirsutism or Ferriman-Gallwey (MFG) score above 8,acne and Male pattern baldness biochemical symptoms of increased endogenesis polycystic ovary (12 or more of 12 follicles per ovary with diameter of 2 to 9 mm , or an increase in ovarian volume to more than 310 ml) Age 20 to 40 years old Having informed written consent
Exclusion criteria
Exclusion criteria: Taking drug of anticoagulants and hyperlipidemia Use of Tobacco Having kidney disease, diabetes, liver disease, cardiovascular disorders, hypothyroidism, inflammatory and rheumatic diseases, hyperprolactinemia, Cushing's syndrome and congenital adrenal hyperplasia Follow a particular diet in the last three months Taking medications that affect insulin sensitivity, inflammation, or lipid profile and hormonal profile, including glucocorticoid drugs, ovulation induction drugs, anti-obesity, anti-diabetes, antihypertensive, estrogenic, anti-androgen, over the past 3 months Unwilling to participate in the study Use of Nutrition Supplements in the last 2 months Pregnancy or breastfeeding Sensitization or allergy to sumac
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Insulin resistance. Timepoint: before intervention and 3 months after intervention. Method of measurement: HOMA-IR method.;Fasting Blood Sugar. Timepoint: before intervention and 3 months after intervention. Method of measurement: colorimetric assay method.;Fasting insulin. Timepoint: Before intervention and 3 months after intervention. Method of measurement: Chemiluminescence assay.;Lipid Profile (LDL, HDL, TG, Total Cholesterol). Timepoint: before intervention AND 3 months after intervention. Method of measurement: colorimetric assay method.;Total Testosterone. Timepoint: before intervention AND 3 months after intervention. Method of measurement: ELIZA method.;DHEA (Dehydroepiandrosterone). Timepoint: before intervention and 3 months after intervention. Method of measurement: ELIZA method.;17-hydroxy Progesterone. Timepoint: before intervention and 3 months after intervention. Method of measurement: ELIZA method.;Androstenedione. Timepoint: before intervention and 3 months after intervention. Method of measurement: ELIZA method.;Luteinizing Hormone (LH). Timepoint: before intervention AND 3 months after intervention. Method of measurement: ELIZA method.;Follicle stimulating hormone(FSH). Timepoint: before intervention and 3 months after intervention. Method of measurement: ELIZA method.;C-reactive protein (hs-CRP). Timepoint: before intervention and 3 months after intervention. Method of measurement: Turbidimetry method.;Hirsutism score. Timepoint: Before intervention AND 3 months after intervention. Method of measurement: Calculation based on Freeman-Gallo method.;Acne. Timepoint: before intervention AND 3 months after intervention. Method of measurement: Face check.;Baldness and hair loss. Timepoint: before intervention AND 3 months after intervention. Method of measurement: Hair Head check. | — |
Secondary
| Measure | Time frame |
|---|---|
| Dietary intake. Timepoint: Before intervention and three months after intervention. Method of measurement: Nutrition 24-hour questionnaire feed and analysis with N4 software.;Anthropometric indicators. Timepoint: Before intervention and three months after intervention. Method of measurement: Meters, scales and Computing.;Physical activity. Timepoint: Before intervention and three months after intervention. Method of measurement: International Physical Activity Questionnaire.;Body fat percentage. Timepoint: Before intervention and three months after intervention. Method of measurement: BIA method with ebody device.;Menstrual cycle order. Timepoint: Before intervention and three months after intervention. Method of measurement: Question from the patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Naheed Aryaeian
Iran University of Medical Sciences
Outcome results
None listed