Urinary Retention. Disorder of urinary system, unspecified
Conditions
Interventions
Intervention 1: As usual anesthetic protocol,10 mg intrathecal bupivacaine 0.5% and 0.1 are injected
immediately, 12mg methyl Naltrexone subcutaneously (by a trained nurse who is unaware of any drugs) will be administered to patients in the first group.
Then during surgery and 24 hours after it, sy
immediately, placebo subcutaneously (by a trained nurse who is unaware of any drugs) will be administered to patients in the second group. Then during surgery and 24 hours after it, symptoms such as u
Prevention
As usual anesthetic protocol,10 mg intrathecal bupivacaine 0.5% and 0.1 are injected
immediately, 12mg methyl Naltrexone subcutaneously (by a trained nurse who is unaware of any drugs) will be administered to patients in the first group.
Then during surgery and 24 hours after it, s
As usual anesthetic protocol,10 mg intrathecal bupivacaine 0.5% and 0.1 are injected
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:18 – 50 years old patient ; planned orthopedic surgery on lower Extremities; usual criteria for spinal anesthesia Exclusion Criteria : Peri-op Int. folley; Genito-urinary problems (Benign prostatic hyperplasia, Urinary stone, Renal failure, … ); Addiction (in 6 mounts before operation) ; Use of opioids in 12 hours before operation; Neurologic Disease (stroke, alcohol/diabete neuropathies, cerebral palsy, spinal lesions, multiple sclerosis, poly myositis ) ; Drugs ( anti-cholinergics, ß-blockers, Sympathomimetics, a-agonists/antagonists)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urinary retention. Timepoint: every 1 hour till 24 hours after surgery. Method of measurement: By a questionnaire of urinary retention: a) the patient's inability to pass urine after surgery, despite feeling a need to urinating for half an hour and leaving every amount of urine after catheterization. B) inability to pass urine for 12 hours after surgery, without feeling a need to urinating and leaving at least 600 cc of urine after catheterization. | — |
Secondary
| Measure | Time frame |
|---|---|
| Itching. Timepoint: every 1 hour till 24 hours after surgery. Method of measurement: By a questionnaire of itching: incidence of itching to the extent that the patient seek treatment.;Nausea, vomiting. Timepoint: every 1 hour till 24 hours after surgery. Method of measurement: By a questionnaire of nausea and vomiting: a) the incidence of nausea in the interval 4 to 24 hours after surgery (each of which is questioned by a trained nurse), b)vomit the stomach contents in 4 to 24 hours after surgery.;Respiratory suppression. Timepoint: every 1 hour till 24 hours after surgery. Method of measurement: By a questionnaire of suppressed breathing, reduced respiratory rate less than 8 per minutes for 24 hours after surgery (each hour can be recorded by trained nurses).;Decreased level of consciousness. Timepoint: every 1 hour till 24 hours after surgery. Method of measurement: By a questionnaire of decreased level of consciousness: drowsiness or dizziness that each hour until 24 hours after surgery are recorded by trained nurses. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSaman Asadi, MD
Shiraz University of Medical Sciences
Outcome results
None listed