Evaluation of pulpal anesthesia with articaine

Evaluation of the success rate of pulpal anesthesia in mandibular first molar following infiltration of 4% Articaine alone and as supplemental injection after inferior alveolar nerve block

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201204109367N2

Enrollment

Registered

2012-04-16

Start date

2012-04-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Local Anesthesia. Local anaesthetics

Interventions

Intervention 1: Control: Inferior alveolar nerve block using 1 Lidocaine cartridge with epinephrine 1/80000. Intervention 2: Intervention1: Buccal infiltration of 1 Articaine cartridge with epinephrin

Control: Inferior alveolar nerve block using 1 Lidocaine cartridge with epinephrine 1/80000

Intervention1: Buccal infiltration of 1 Articaine cartridge with epinephrine 1/100000

Intervention 2: Buccal infiltration of 2 Articaine cartridge with epinephrine 1/100000

Intervention 3: Inferior alveolar nerve block using 1 Lidocaine cartridge with epinephrine 1/80000+Buccal infiltration of 1 Articaine cartrdige with epinephrine 1/100000

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients aged between 18-55 years old who have at least 1 vital first mandibular molar without any restoration or decay Exclusion criteria: 1.paitients with systemic conditions which eliminate the use of epinephrine. 2.history of allergy to amide anesthetics or contents of local anesthetic cartrige. 3. pregnant women and 4. use of algesics, opioides or any other drugs which influence the anesthesia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Success rate. Timepoint: Each 3 minutes after injection. Method of measurement: With electric pulp tester(EPT).;Onset of anesthesia. Timepoint: Each 3 minutes after injection. Method of measurement: With electric pulp tester(EPT).;Duration of anesthesia. Timepoint: Each 3 minutes after onset of anesthesia. Method of measurement: With electric pulp tester(EPT).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Kaveh Oloomi

Endodontics Department- Faculty of Dentistry- Tehran University of Medical Sciences

koloomi@yahoo.com+98 21 8835 1173

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026