Glioblastoma multiforme. Malignant neoplasm of brain
Conditions
Interventions
Intervention 1: Intervention group: is the group of patients whose will receive the restricted ketogenic diet. patients are admitted in Shariati hospital-neurosurgery ward. Medical history, physical e
Treatment - Drugs
Treatment - Other
Intervention group: is the group of patients whose will receive the restricted ketogenic diet. patients are admitted in Shariati hospital-neurosurgery ward. Medical history, physical examination, KPS
Control group contains 10 patients whose will not receive the ketogenic diet
Sponsors
Vice chancellor for research, Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 149 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1- Patient age >49 years 2- KPS (Karnofsky Performance Scale) >69 3- Patient had to be operated for brain tumor and Pathology is primary glioblastoma multiforme 4- Patient has underwent fractionated radiotherapy for his tumor 5- Patient has received chemotherapy course using Temozolomide Exclusion criteria: 1- Other diagnosis is suspected 2- Patient could not tolerated the ketogenic diet 3- Ketogenic diet is contraindicated (Pyruvate carboxylase deficiency, Porphyria and Congenital fat metabolism disorders) 4- Patient does not agreed with the regime protocol
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient's survival. Timepoint: Every 3 months up to death. Method of measurement: Weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life. Timepoint: Every 3 months. Method of measurement: Assessed by FIM Form. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Seyyed Mohamad Ghodsi
Tehran university of medical sciences
Outcome results
None listed