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The effect of tolterodine and gabapentin in reducing pain and discomfort after surgery

Comparison the effect of tolterodine and gabapentin in reducing pain and discomfort of catheter after Percutaneous nephrolithotomy surgery at Hashemi Nejad Hospital

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT201204066504N3
Enrollment
96
Registered
2016-12-07
Start date
2016-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nephrolithiasis. Calculus of urinary tract in other diseases classified elsewhere

Interventions

Intervention 1: The placebo group includes people who feel discomfort after PCNL in the lumen of the catheter after extubation are taking opioid analgesic drug 25 mg per injection. Intervention 2: Int
Placebo
Treatment - Drugs
The placebo group includes people who feel discomfort after PCNL in the lumen of the catheter after extubation are taking opioid analgesic drug 25 mg per injection.
Intervention: Group 1 consists of people who are taken tolterodine 2mg orally 1 hour before surgery with a little water.
Intervention: Group 2 are taken Gabapentin 600mg (2 capsules Gabapentin 300mg) 1 hour before the surgery. Also, all the people who feel pain and discomfort during the study was prescribed analgesic 2

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: PCNL surgery candidate; Older than 18 years old; Risk of anesthesia was ASA 1 Exclusion criteria: Alchohol or drug abuse; Sensetivity to gabapentin, tolterodine or opioids; Using opioids 12 hour before syrgery; Any confounding medical or psychological situation of patients

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain of cathetring. Timepoint: 1,3,6,12 and 24 hours after PCNL surgery. Method of measurement: Visual analouge scale questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Saeed Farhadi Niaki

Faculty of medicine

saeed.niaki@gmail.com+91 11270765

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026