Vitamin D effect on reduction of proteinuria in patients with diabetic nephropathy and vitamin d deficiency

Evaluation of vitamin D effect on reduction of proteinuria in patients with diabetic nephropathy and vitamin d deficiency

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201204049374N1

Enrollment

Registered

2012-08-07

Start date

2011-12-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetic nephropathy. non insulin dependent diabet mellitus

Interventions

Intervention 1: intervention: vitamin D pearl

50000 unit, once weekly to 12 weeks. Intervention 2: control:placebo pearl, once weekly to 12 weeks.

Treatment - Drugs

control:placebo pearl, once weekly to 12 weeks

intervention: vitamin D pearl

50000 unit, once weekly to 12 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: having type 2 diabetes; diabetic nephropathy; vitamin D deficiency; GFR> 60 and recieving stable doses of ACE inhibitors or ARBs for 3 months or more. Exclusion criteria: glomerulonephritis; serum phosphorus level greater than 5.2 mg/dL; serum calcium level (adjusted for albumin) greater than 10.0 mg/dL; active malignancy;likelihood of requiring renal replacement therapy within 1 year or uncontrolled hypertension.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Urine albomin/ creatinin ratio. Timepoint: Before intervention and 3 and 6 months after intervention. Method of measurement: urine Alb/cr (mg/ gr).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNooshin Ahmadi

Isfahan University of Medical Sciences

nooshinahmadi@resident.mui.ac.ir

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026