major depressive disorder. Mild depressive episode- Moderate depressive episode
Conditions
Interventions
Intervention 1: first group: cap fluoxetine 30 mg/day with cap hidroalcoholic extract of saffron 40 mg bid for 4 weeks. Intervention 2: Second group: cap fluoxetine 30 mg/day with cap hidroalcoholic e
Treatment - Drugs
first group: cap fluoxetine 30 mg/day with cap hidroalcoholic extract of saffron 40 mg bid for 4 weeks
Second group: cap fluoxetine 30 mg/day with cap hidroalcoholic extract of saffron 80 mg bid for 4 weeks
Sponsors
Research comittee of Mazandaran university of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: inclusion criteria: age range between 20 to 50 years; absence of psychosis; absence of manic episodes or BMD; negative history of mental retardation;negative history of general medical condition; negative history of drug dependency; nagative history of antidepressant drug use four weeks before study; Psychotherapic treatment simultaneously. exclusion criteria: pregnancy; risk of suicide.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of depression. Timepoint: first, 14th and 28th day of treatment. Method of measurement: Hamilton Deoression scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMozhgan Amini
Psychiatric and behavioral research center of Mazandaran University of Medical Sciences
Outcome results
None listed