Post-treatment pain after root canal therapy. Diseases of pulp and periapical tissues
Conditions
Interventions
Intervention 1: Intervention:
saffron with dose of 100 mg in each capsule every 6 hours up to 48 hours (400 mg/day). Intervention 2: Control:starch with dose of 100 mg in each capsule every 6 hours up
Treatment - Drugs
Placebo
Intervention:
saffron with dose of 100 mg in each capsule every 6 hours up to 48 hours (400 mg/day)
Control:starch with dose of 100 mg in each capsule every 6 hours up to 48 hours (400 mg/day)
Sponsors
Zahedan University of Medical Scienves, Vice-chencellor for research
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: vital teeth with one root canal and moderate to severe pain and patients over 18 years old with at least high school education Exclusion criteria: teeth with periapical lesions; patients with history of allergy to saffron; diabetes mellitus, cardiovascular disorders, kidney and liver diseases, blood and hormonal disorders and electrolyte imbalance; women in pregnancy or breast feeding period and use of analgesics or opioids during 4 hours before treatment.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity. Timepoint: Every 6 hours after treatment completion up to 48 hours. Method of measurement: Visual Analog Scale(VAS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Kaveh Oloomi
Endodontics Department- Faculty of Dentistry- Tehran University of Medical Sciences
Outcome results
None listed