Comparison of hemodynamic effects of biventricular versus left ventricular only pacing in patients receiving Cardiac Resynchronization Therapy (CRT)

Comparison of hemodynamic effects of biventricular versus left ventricular only pacing in patients receiving cardiac resynchronization therapy: a before-after clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201203169014N7

Enrollment

Registered

2012-07-02

Start date

2012-07-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cadiac Resynchronization Therapy (CRT). Other cardiac arrhythmias

Interventions

Intervention 1: In intervention group, the CRT pacemaker will be set for left ventricular only pacing for three months. Intervention 2: In control group, the CRT pacemaker will be left as biventricula

Treatment - Devices

In intervention group, the CRT pacemaker will be set for left ventricular only pacing for three months

In control group, the CRT pacemaker will be left as biventricular pacing for three months

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients with CRT will be included unless they have not responded to CRT.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Four variables will be considered for assessing hemodynamic status of the patientsat baseline, three and six month later including: (a) Velocity Time Integral (VTI) of aortic valve per cm; (b) Left Ventricular End Diastolic Voliume (LVEDV) of aortic valve per mL/m2; (c) Left Ventricular End Systolic Voliume (LVESV) of aortic valve per mL/m2; (d) Left Ventricular Ejection Fraction (LVEF) of aortic valve per percent. Timepoint: 3 months. Method of measurement: Ecocardiography.	—

Measure

Time frame

Four variables will be considered for assessing hemodynamic status of the patientsat baseline, three and six month later including: (a) Velocity Time Integral (VTI) of aortic valve per cm; (b) Left Ventricular End Diastolic Voliume (LVEDV) of aortic valve per mL/m2; (c) Left Ventricular End Systolic Voliume (LVESV) of aortic valve per mL/m2; (d) Left Ventricular Ejection Fraction (LVEF) of aortic valve per percent. Timepoint: 3 months. Method of measurement: Ecocardiography.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactJalal Poorolajal

Research Center for Health Sciences, Department of Epidemiology & Biostatistics

poorolajal@umsha.ac.ir+98 81 1838 0090

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026