Attention deficit hyperactivity disorder. Attention-deficit hyperactivity disorders
Conditions
Interventions
Intervention 1: Intervention group: receive vitamin A+D drop with a dose of 400 unit/day for vitamin D for 12 weeks along with their standard therapeutic regimen. Intervention 2: Control group: recei
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
7 Years to 14 Years
Inclusion criteria
Inclusion criteria: 7-14 years old children diagnosed attention deficit hyperactivity disorder children by two psychiatrists and based on DSM-V Without vitamin D deficiency (Serum 25(OH) vitamin D levels above 30ng/ml) All patients are on standard treatment regimen for attention-deficit hyperactivity disorder for at least 3 months and a stable dose for at least 1 month
Exclusion criteria
Exclusion criteria: Acute relapse Psychiatric comorbidity as defined by DSM-V Mental retardation Neurological diseases such as delirium, seizure, traumatic brain injury Current significant unstable medical illness Hypersensitivity to vitamin D Previous treatment with any products enriched with vitamin D at least 2 months before the initiation Unwillingness of the patient or his guardian to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The scores of emotional and behavioral problems in Strengths and Difficulties Questionnaire. Timepoint: At baseline and days 45 and 90 of the baseline. Method of measurement: Strengths and Difficulties Questionnaire (SDQ).;The scores of symptoms of hyperactivity, impulsivity and cognitive impairment of ADHD in Parent's Rutter Questionnaire. Timepoint: At baseline and days 45 and 90 of the baseline. Method of measurement: Parent's Rutter questionnaire.;The scores of symptoms of hyperactivity, impulsivity and cognitive impairment of ADHD in Conners' Parent Rating Scale. Timepoint: At baseline and days 45 and 90 of the baseline. Method of measurement: Conners' Parent Rating Scale.;Serum 25(OH) vitamin D level. Timepoint: At baseline and day 90 from baseline. Method of measurement: ELISA Kit.;Side effects of vitamin D. Timepoint: At baseline and days 45 and 90 of the baseline. Method of measurement: Side effects checklist and Serum 25(OH) vitamin D level. | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: At baseline and day 90 from baseline. Method of measurement: Scales.;Waist circumference. Timepoint: At baseline and day 90 from baseline. Method of measurement: Tape.;Body mass index. Timepoint: At baseline and day 90 from baseline. Method of measurement: Using the formula kilograms per square meter of height(Kg/m2).;Serum total cholesterol level. Timepoint: At baseline and day 90 from baseline. Method of measurement: Laboratory kit.;Serum Low-density lipoprotein(LDL) level. Timepoint: At baseline and day 90 from baseline. Method of measurement: Laboratory kit.;Serum High density lipoprotein (HDL) level. Timepoint: At the baseline and on the 90th day. Method of measurement: Laboratory kit.;Serum triglyceride level. Timepoint: At the baseline and on the 90th day. Method of measurement: Laboratory kit.;Serum fasting blood sugar level. Timepoint: At the baseline and on the 90th day. Method of measurement: Laboratory kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNarjes Hendouei
Mazandaran University of Medical Sciences
Outcome results
None listed