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Comparison of analgesic effects of paracetamol and morphine infusion after elective laparotomy surgeries

Comparison of analgesic effects of paracetamol and morphine infusion after elective laparotomy surgeries

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201203114969N6
Enrollment
112
Registered
2012-04-09
Start date
2010-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain. ------

Interventions

Intervention 1: Intravenous infusion of 20 mg morphin during 24 hours after surgery. Intervention 2: Intravenous infusion of4 gr paracetamol during 24 hours after surgery.
Treatment - Drugs
Intravenous infusion of 20 mg morphin during 24 hours after surgery
Intravenous infusion of4 gr paracetamol during 24 hours after surgery

Sponsors

Tehran University of Medical Sciense
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:1-ASA I,II patients, 2-age between 20 to 50 years old, 3- elective laparotomy surgeries, 4-duration of surgery less than 3h , 5-no opium addiction, 6- no history of prolonged analgesic or sedative consumption, 7- no history of cardiac or pulmonary disease, 8- no thyroid or hepatic dysfunction, 9- no history of allergy to morphine and paracetamol. exclusion criteria:1- serious disgusting complications such as nausea, vomiting or itching, 2- no patient satisfaction of analgesic protocol and need to inject analgesic more than usual, 3- severe hepatic or respiratory complications.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Postoperative pain. Timepoint: 2, 4, 6, 12 and 24 hours after surgery. Method of measurement: Visual Analog Scale from 1 to 10.

Secondary

MeasureTime frame
Itching. Timepoint: During 24 hours after surgery. Method of measurement: Medical records and asking the patients.;Nausea and vomiting. Timepoint: During 24hours after surgery. Method of measurement: Medical records and asking the patients.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026