Determination of mgso4 infusion effect for treatment of patient with acute pulmonary edema arrived rasol and sina hospital from khordad 1391 to khordad 1392

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201203089235N1

Enrollment

Registered

2012-10-16

Start date

2012-06-05

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute pulmonary edema. with mention of heart disease NOS or heart failure

Interventions

Intervention 1: In intervention group start treatment by o2 until o2Sat of patient >94% (minimum by 4 lit/min o2),plus Amp lasix 1 mgr/kg and Amp nitroglycerin 5 mic gr/min started and titrated 5 mic

Treatment - Drugs

In intervention group start treatment by o2 until o2Sat of patient >94% (minimum by 4 lit/min o2),plus Amp lasix 1 mgr/kg and Amp nitroglycerin 5 mic gr/min started and titrated 5 mic gr/min if patie

In control group start treatment by o2 until o2Sat of patient >94% (minimum by 4 lit/min o2),Amp lasix 1 mgr/kg and Amp nitroglycerin by 5 mi cgr/min started and titrated 5 mi cgr/min if patients bloo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria:patient with acute pulmonary edema Exclusion criteria:presence of mgso4 side effects

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Hospitalization duration. Timepoint: for 6 hours after trial initation. Method of measurement: Compare of hospitalization duration in two groups.;Dysrhythmia incidence that should be treat in ED. Timepoint: for 6 hours after trial initation. Method of measurement: Compare of demand to intubation in two groups.;Necessary for intubation. Timepoint: for 6 hours after trial initation. Method of measurement: Compare of incidence of dysrhytmia that demand treatment in two groups.;Improvement both SaO2 and dyspnea score(verbal quantitative scale) in 6 hours after treatment initiation. Timepoint: for 6 hours after trial initation. Method of measurement: Compare of Sao2 improvement more than 94% and dyspnea score (by verbal quantitative scale pathway) for 6 hours after treatment initiation in two groups.	—

Measure

Time frame

Hospitalization duration. Timepoint: for 6 hours after trial initation. Method of measurement: Compare of hospitalization duration in two groups.;Dysrhythmia incidence that should be treat in ED. Timepoint: for 6 hours after trial initation. Method of measurement: Compare of demand to intubation in two groups.;Necessary for intubation. Timepoint: for 6 hours after trial initation. Method of measurement: Compare of incidence of dysrhytmia that demand treatment in two groups.;Improvement both SaO2 and dyspnea score(verbal quantitative scale) in 6 hours after treatment initiation. Timepoint: for 6 hours after trial initation. Method of measurement: Compare of Sao2 improvement more than 94% and dyspnea score (by verbal quantitative scale pathway) for 6 hours after treatment initiation in two groups.

—

Secondary

Measure	Time frame
Decrease respiratory rate under 8/min. Timepoint: for 6 hours from tretment initation. Method of measurement: Account respiratory rate in 1 minute.;Diminish of deep tendon reflex. Timepoint: for 6 hours after treatment initation. Method of measurement: Monitoring of deep tendon reflex.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Seyyed Mahdi Zia Ziabari M.D

Tehran university medical scince

smzz592000@yahoo.com+98 21 6652 5327

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026