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Trans-dermal Fentanyl patch compared to intravenous morphine, efficacy on post thoracotomy pain

Trans-dermal Fentanyl patch compared to intravenous morphine, efficacy on post thoracotomy pain

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201203067752N2
Enrollment
50
Registered
2012-03-17
Start date
2009-05-25
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative thoracic surgery pain management. Postprocedural respiratory disorder, unspecified

Interventions

Intervention 1: In intervention group : One hour prior to general anesthesia induction, a TFP (Duragesic 50 µg/h) was placed on anterolateral skin of the thorax . Intervention 2: In control group: 4
Treatment - Drugs
In intervention group : One hour prior to general anesthesia induction, a TFP (Duragesic 50 µg/h) was placed on anterolateral skin of the thorax .
In control group: 4 mg of IV morphine sulfate was every 6 hours after thoracotomy

Sponsors

Vice-chancellor of research of Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:Patients with ASA class I and II; who were candidates forelective thoracic surgery. Exclusion criteria History of allergies or hypersensitivity to opioid; addiction to alcohol or narcotics; dementia; psychological disorders; skin diseases that preventing the absorption oftransdermal fentanil patch ; pregnant or breast-feeding mothers; the patients undergoing intra pleural or intercostals blockage.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Postoperative paine. Timepoint: 72 hours postoperative. Method of measurement: Visual Analog Scale.;The amount of Morphine. Timepoint: 72 hours postoperative. Method of measurement: miligram.

Secondary

MeasureTime frame
Systolic Blood Pressure. Timepoint: 72 h postoperative. Method of measurement: mm/Hg.;Diaystolic Blood Pressure. Timepoint: 72 h postoperative. Method of measurement: mm/Hg.;?Respiratory depression. Timepoint: 72 h postoperative. Method of measurement: Respiratory rate for min.;Heart Rate. Timepoint: 72 h postoperative. Method of measurement: Heart Rate for 1 min.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmrimaleh, Parviz

Babol University of Medical Sciences

pamrimaleh@yahoo.com+98 11 1223 8296

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026