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Effects of creatine supplementation in athletes

The effect of creatine and carnitine supplementation on anaerobic performance, energy metabolism, inflammatory markers, oxidative stress and kidney function in athletes

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201203063236N3
Enrollment
48
Registered
2012-03-14
Start date
2011-12-11
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Athletes. Routine general health check-up of defined subpopulation

Interventions

Intervention 1: Placebo (MCC mixed with cellulose) 8 g daily (4 times daily) for 28 days. Intervention 2: Supplementation with creatine and carnitine ( 0.3 g / kg / d to 7 days, and 0.03 g / kg / d to
Placebo
Placebo (MCC mixed with cellulose) 8 g daily (4 times daily) for 28 days
Supplementation with creatine and carnitine ( 0.3 g / kg / d to 7 days, and 0.03 g / kg / d to 21 days followed by addition 2 g/d for every 28 days)
20 to 30 grams of creatine monohydrate supplementation (0.3 grams per kilogram of body weight) for 7 days (loading period) 2 to 5 grams to 21 days later (maintain period)
Carnitine supplementation 2 g daily for 28 days

Sponsors

Shiraz university of medical sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: male athletes, martial artist who recently have started this exercise. Age between 18 and 30 years, no history of liver disease, cardio - vascular or muscular problems - musculoskeletal, pulmonary, and not receiving any type of protein supplement during the last few months. Exclusion criteria from the study: During the supplementation period, someone with a cold or diarrhea will be excluded

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Anaerobic performance. Timepoint: Before and after intervention. Method of measurement: Menarche bike model E894.;Triglyceride. Timepoint: Before and after intervention. Method of measurement: Colorimetric method with an autoanalyzer system.;Lactic Acid. Timepoint: Before and after intervention. Method of measurement: Spectrophotometrically with spectrophotometry.;Interleukin-6. Timepoint: Before and after intervention. Method of measurement: Spectrophotometry with RIA.;Glutathione peroxidase. Timepoint: Before and after intervention. Method of measurement: ELISA using ELISA kits.;Malondialdehyde. Timepoint: Before and after intervention. Method of measurement: Spectrophotometrically with spectrophotometry.;Creatinine. Timepoint: Before and after intervention. Method of measurement: Colorimetric method with an autoanalyzer system.;BUN. Timepoint: Before and after intervention. Method of measurement: Colorimetric method with an autoanalyzer system.;24-hour urine creatinine. Timepoint: Before and after intervention. Method of measurement: Colorimetric method with an autoanalyzer system.

Secondary

MeasureTime frame
Overweight. Timepoint: Before and after intervention. Method of measurement: By Libra.;Weight loss. Timepoint: Before and after intervention. Method of measurement: By Libra.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBahman Panahandeh

School of health & nutrition, Shiraz University of Medical Sciences

panahande.b@gmail.com+98 71172510018

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026