pruritus. Pruritus, unspecified
Conditions
Interventions
Intervention 1: group1 : 20 mg propofol is injected as bolus ,then 50 mcg/kg/min IV infusion. Intervention 2: group2 :midazolam:
0.03 mg/kg midazolam is injected as bolus dose,then 0.02 mcg/kg/min IV
Prevention
group1 : 20 mg propofol is injected as bolus ,then 50 mcg/kg/min IV infusion.
group2 :midazolam:
0.03 mg/kg midazolam is injected as bolus dose,then 0.02 mcg/kg/min IV infusion
group3:
10 mg propofol and 0.015 mg/kg midazolam are injectes as bolus doses , then 25 mcg/kg/min propofol and 0.01 mcg/kg/min midazolam IV infusion.
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: inclusion criteria: age:18-65 each sex; elective surgery; major surgery ; ASA class 1 or 2; informed cosent exclusion criteria: spinal anesthesia contraindication; opium addicted patients; emergent surgery; severe COPD; drug allergy to used drug in this study
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pruritus. Timepoint: 24 hours after begining the surgery. Method of measurement: questioning the patient about the time, area and the severity of itching. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Jalil Makarem
Tehran University of Medical Sciences
Outcome results
None listed