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Randomized clinical trial of standardized topical formula containing standard extracts of Arnebia euchroma, Malva sylvestris and sesame oil (less than 20%) vs. Silversulfadiazine cream on wound healing in 2nd degree burns

Randomized clinical trial of standardized topical formula containing standard extracts of Arnebia euchroma, Malva sylvestris and sesame oil (less than 20%) vs. Silversulfadiazine cream on wound healing in 2nd degree burns

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201203059204N1
Enrollment
50
Registered
2014-04-28
Start date
2012-07-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

provides a standard herbal formulation to heal burn wounds. Burn and corrosion of trunk -Burn and corrosion of shoulder and upper limb -Burn and corrosion of wrist and hand -Burn and corrosion of hip and lower limb, except ankle and foot -Burn and corrosion of ankle and foot

Interventions

Intervention 1: Intervention: Dressing with patented topical herbal formulation containing extracts of Arnebia euchroma, Malva sylvestris and sesame oil (less than 20%) after disinfection of wounds ac
Treatment - Drugs
Intervention: Dressing with patented topical herbal formulation containing extracts of Arnebia euchroma, Malva sylvestris and sesame oil (less than 20%) after disinfection of wounds according to stand
Control group: Dressing the wounds using silver sulfadiazine manufactured by Sobhan Pharmaceutical company after disinfection of wounds according to standard method every other day by physician in hos

Sponsors

Vice-Chancellor for Research, Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:Patients aged between 20 to 60 years old; 2nd degree burn wounds; burn surface area up to 5% Exclusion criteria: Epilepsy;Diabetes; Cardiovascular diseases; pregnancy; Breast feeding; electrical and respiratory burns

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Wound healing time. Timepoint: daily. Method of measurement: time between admission and epithelialization or preparation for skin graft.;Surface area of wounds needed to be grafted. Timepoint: daily. Method of measurement: by ruller.

Secondary

MeasureTime frame
Allergy to applied treatment - infection. Timepoint: 21day. Method of measurement: visit by expert physician.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ali Akbar Mohammadi

Shiraz University of Medical Sciences

mohamadiaa@sums.ac.ir; burnres1@sums.ac.ir+98 71 1820 8880

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026