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Comparison of efficacy of topical clobetasol 0.05% plus 5FU 5% cream vs. topical clobetasol 0.05% alone in the treatment of vitiligo.

Comparison of efficacy of topical clobetasol 0.05% plus 5FU 5% cream vs. topical clobetasol 0.05% alone in the treatment of vitiligo.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201203049198N2
Enrollment
45
Registered
2012-04-01
Start date
2009-10-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitiligo. vitiligo

Interventions

Intervention 1: In control group: Clobetasol 0.05% cream for topical use over the selected lesion on the left side of the body was given to patient . we recommended that patient use the drug every
Treatment - Drugs
In control group: Clobetasol 0.05% cream for topical use over the selected lesion on the left side of the body was given to patient . we recommended that patient use the drug every other day,once
In interventionl group: Clobetasol 0.05% cream plus 5FU5% cream for topical use over the selected lesion on the right side of the body was given to patient . we recommended that patient use the drug

Sponsors

Isfahan Univercity of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
17 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria were as follow: vitiligo patients with at least 2 lesions on the body, >15 years old, lack of follicular pigmentation (score=0), lack of white hair over the lesion and disease stability within the last 6 months. Exclusion criteria were as follow: those who had recieved topical medication for at least 1 month and systemic medication or phototherapy for at least 3 months prior to inclusion; past medical history of liver, kidney and hematologic disorders; the vitiligo lesions on the face, genitalia or acral areas; pregnancy or lactation and the segmental subtype. Patients were instructed about the study protocol, possible side effects and a written informed consent was taken from all patients before enrollment.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Lesion of vitiligo. Timepoint: End of three months. Method of measurement: Pigmentation score.

Secondary

MeasureTime frame
Erythema,atrophy,erosion. Timepoint: any time during treatmrnt. Method of measurement: observation.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactdr.zabihollah shahmoradi

Isfahan Univercity of Medical Sciences

shahmoradi@mui.ac.ir+98 31 1666 6666

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026